Cyclic GMP–AMP signalling protects bacteria against viral infection

Another project which MS-Omics has contributed to.

D Cohen, S Melamed, A Millman, G
Shulman… Gil Amitai & Rotem Sorek – Nature, 2019 –



The cyclic GMP–AMP synthase (cGAS)–STING pathway is a central component of the
cell-autonomous innate immune system in animals1,2. The cGAS protein is a
sensor of cytosolic
viral DNA and, upon sensing DNA, it produces a cyclic GMP–AMP (cGAMP)
signalling molecule … 

Read the article here.

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